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ruvector/examples/dna/src
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Claude 9eb6e3364d feat(rvdna): add PCSK9 rs11591147 protective cardiovascular SNP 
Add PCSK9 R46L loss-of-function variant (NEJM 2006: OR 0.77 CHD,
0.40 MI) as a protective cardiovascular SNP with negative weights.
Include PCSK9→LDL-C biomarker correlation (15-21% lower LDL in
carriers). Refactor gene-biomarker correlations from match to
additive if-chain so multiple gene effects can stack on the same
biomarker (e.g., APOE raises LDL while PCSK9 R46L lowers it).
Panel expanded to 20 SNPs.

https://claude.ai/code/session_014FpaYVohmyLH5dcBZTgmSY
2026-02-22 06:44:14 +00:00
..
alignment.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
biomarker.rs feat(rvdna): add PCSK9 rs11591147 protective cardiovascular SNP 2026-02-22 06:44:14 +00:00
biomarker_stream.rs refactor(rvdna): consolidate SNP arrays, cache metadata, optimize streaming 2026-02-22 06:31:44 +00:00
epigenomics.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
error.rs feat(rvdna): native 23andMe genotyping pipeline v0.2.0 2026-02-20 20:40:51 +00:00
genotyping.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
health.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
kmer.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
kmer_pagerank.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
lib.rs feat(rvdna): add health biomarker analysis engine with streaming simulation 2026-02-22 05:19:23 +00:00
main.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
pharma.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
pipeline.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
protein.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
real_data.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
rvdna.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
types.rs fix: apply cargo fmt across workspace and fix CI issues 2026-02-21 20:56:38 +00:00
variant.rs feat(dna): implement missing capabilities + optimize hot paths 2026-02-11 05:31:16 +00:00