ruvector/docs/research/DrAgnes
rUv 1ab5240956 feat: ADR-119 historical crawl evolutionary comparison
Implement temporal knowledge evolution tracking across quarterly
Common Crawl snapshots (2020-2026). Includes:
- ADR-119 with architecture, cost model, acceptance criteria
- Historical crawl import script (14 quarterly snapshots, 5 domains)
- Evolutionary analysis module (drift detection, concept birth, similarity)
- Initial analysis report on existing brain content (71 memories)

Cost: ~$7-15 one-time for full 2020-2026 import.

Co-Authored-By: claude-flow <ruv@ruv.net>
2026-03-22 00:28:13 +00:00
..
architecture.md docs: DrAgnes project overview and system architecture research 2026-03-21 20:58:43 +00:00
competitive-analysis.md docs: DrAgnes competitive analysis and deployment plan research 2026-03-21 21:08:15 +00:00
crawl-phase1-benchmark.md docs: Common Crawl Phase 1 benchmark — pipeline validation results 2026-03-22 00:09:19 +00:00
data-sources.md docs: DrAgnes HIPAA compliance strategy and data sources research 2026-03-21 21:01:41 +00:00
deployment.md docs: DrAgnes competitive analysis and deployment plan research 2026-03-21 21:08:15 +00:00
dermlite-integration.md docs: DrAgnes DermLite integration and 25-year future vision research 2026-03-21 21:05:05 +00:00
evolution-analysis.md feat: ADR-119 historical crawl evolutionary comparison 2026-03-22 00:28:13 +00:00
future-vision.md docs: DrAgnes DermLite integration and 25-year future vision research 2026-03-21 21:05:05 +00:00
HAM10000_analysis.md data(dragnes): HAM10000 metadata and analysis script 2026-03-21 22:06:45 +00:00
HAM10000_stats.json data(dragnes): HAM10000 metadata and analysis script 2026-03-21 22:06:45 +00:00
hipaa-compliance.md docs: DrAgnes HIPAA compliance strategy and data sources research 2026-03-21 21:01:41 +00:00
README.md docs: DrAgnes project overview and system architecture research 2026-03-21 20:58:43 +00:00

DrAgnes: AI-Powered Dermatology Intelligence Platform

Status: Research & Planning Date: 2026-03-21 Project: RuVector DrAgnes Initiative

Vision

DrAgnes is an AI-powered dermatology intelligence platform that transforms skin lesion detection, classification, and clinical decision support. Built on the RuVector cognitive substrate, it combines DermLite dermoscopic imaging hardware with MobileNetV3 CNN classification, pi.ruv.io collective brain learning, and the RuVocal chat interface to create a system that learns from every diagnosis, improves with every practice that adopts it, and operates with full HIPAA compliance.

The name "DrAgnes" is a portmanteau of "Dermatology" + "Agnes" (from the Greek "hagne," meaning pure/sacred) -- reflecting the platform's commitment to pure, evidence-based diagnostic intelligence.

Why This Matters

  • Melanoma kills 8,000 Americans annually. Early detection reduces mortality by 90%. Yet dermatologist wait times average 35 days in the US, and rural areas have virtually no access to dermatoscopy expertise.
  • Existing AI tools are static. They train once on a fixed dataset and never improve. DrAgnes learns continuously from every participating practice while preserving patient privacy through differential privacy and PII stripping.
  • Dermoscopy is underutilized. Only 48% of US dermatologists use dermoscopy regularly. DrAgnes makes dermoscopic analysis accessible to primary care physicians, nurse practitioners, and telemedicine providers via a simple phone camera + DermLite adapter.

Core Differentiators

  1. Collective Intelligence: Every diagnosis enriches the pi.ruv.io brain's knowledge graph. De-identified embeddings (never raw images) flow into a shared model that benefits all practices. A rural clinic in Montana learns from a university hospital in Boston without ever seeing a patient record.

  2. Offline-First Architecture: The WASM-compiled CNN runs entirely in the browser. No internet required for classification. The brain syncs opportunistically when connectivity is available.

  3. Provenance & Trust: Every diagnostic suggestion carries a SHAKE-256 witness chain proving which model version, which training data epoch, and which knowledge graph state produced it. Full reproducibility for clinical audits.

  4. Practice-Adaptive Learning: SONA MicroLoRA (rank-2) adapts the base model to each practice's patient population using EWC++ regularization to prevent catastrophic forgetting. A practice in equatorial Africa sees different lesion distributions than one in Scandinavia -- DrAgnes adapts accordingly.

  5. DermLite-Native: Purpose-built integration with DermLite HUD, DL5, DL4, and DL200 devices. Supports polarized and non-polarized dermoscopy, contact and non-contact imaging, and automated ABCDE scoring.

Platform Stack

Layer Technology Purpose
Frontend SvelteKit + TailwindCSS (RuVocal) PWA with camera API, offline support
CNN Engine ruvector-cnn (MobileNetV3 Small) 576-dim embeddings, INT8 quantized
WASM Runtime ruvector-cnn-wasm Browser-native inference, SIMD128
Knowledge Graph pi.ruv.io brain 1,500+ memories, 316K edges, PubMed
Search HNSW + PiQ3 quantization Sub-millisecond nearest neighbor
Learning SONA MicroLoRA + EWC++ Online adaptation per practice
Privacy PII stripping + differential privacy epsilon=1.0, HIPAA compliant
Provenance Witness chains (SHAKE-256) Audit trail for every prediction
Storage Firestore + GCS + RVF containers De-identified metadata only
Deployment Google Cloud Run + Firebase Hosting Multi-region, auto-scaling

Research Documents

Document Description
Architecture System architecture, data flow, integration points
HIPAA Compliance Privacy, security, regulatory compliance strategy
Data Sources Training datasets, medical literature, enrichment sources
DermLite Integration Device capabilities, image capture, dermoscopic analysis
Future Vision 25-year forward roadmap (2026-2051)
Competitive Analysis Market landscape and DrAgnes differentiation
Deployment Google Cloud deployment plan, cost model
  • ADR-117: DrAgnes Dermatology Intelligence Platform (this project)
  • ADR-091: INT8 CNN Quantization
  • ADR-088: CNN Contrastive Learning
  • ADR-089: CNN Browser Demo
  • ADR-116: Spectral Sparsifier Brain Integration

Clinical Disclaimer

DrAgnes is designed as a clinical decision support tool, not a diagnostic replacement. All classifications must be reviewed by a qualified healthcare professional. DrAgnes does not provide medical diagnoses and should not be used as the sole basis for clinical decisions. The platform is designed to augment, not replace, dermatological expertise.