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ruvector/examples/dna/adr
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Claude d7efab34c5 feat(rvdna): add npm biomarker engine with risk scoring, streaming, and benchmarks 
ADR-015: Pure-JS biomarker engine mirroring Rust biomarker.rs and
biomarker_stream.rs exactly. Includes:

- src/biomarker.js: 20-SNP composite risk scoring, 6 gene-gene
  interactions, 64-dim L2-normalized profile vectors, synthetic
  population generation with Mulberry32 PRNG
- src/stream.js: RingBuffer, StreamProcessor with Welford online
  stats, CUSUM changepoint detection, z-score anomaly detection,
  linear regression trend analysis, batch reading generation
- tests/test-biomarker.js: 35 tests + 5 benchmarks covering all
  classification levels, risk scoring, vector encoding, population
  generation, streaming, anomaly/trend detection
- index.d.ts: Full TypeScript definitions for all biomarker APIs
- package.json: Bump to v0.3.0, add biomarker keywords

Benchmark results (Node.js):
  computeRiskScores: 7.33 us/op
  encodeProfileVector: 9.51 us/op
  RingBuffer push+iter: 3.32 us/op

https://claude.ai/code/session_014FpaYVohmyLH5dcBZTgmSY
2026-02-22 15:27:37 +00:00
..
.gitkeep feat(dna): scaffold DNA analyzer example with claude-flow init 2026-02-11 00:25:19 +00:00
ADR-001-vision-and-context.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-002-quantum-genomics-engine.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-003-genomic-vector-index.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-004-genomic-attention-architecture.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-005-graph-neural-protein-engine.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-006-temporal-epigenomic-engine.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-007-distributed-genomics-consensus.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-008-wasm-edge-genomics.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-009-variant-calling-pipeline.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-010-quantum-pharmacogenomics.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-011-performance-targets-and-benchmarks.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-012-genomic-security-and-privacy.md feat(dna): optimize all 12 ADRs + add DDD docs, README 2026-02-11 04:02:06 +00:00
ADR-013-rvdna-ai-native-format.md feat(dna): add RVDNA AI-native format, real gene data, 8-stage pipeline 2026-02-11 04:48:28 +00:00
ADR-014-health-biomarker-analysis.md feat(rvdna): add health biomarker analysis engine with streaming simulation 2026-02-22 05:19:23 +00:00
ADR-015-npm-wasm-biomarker-engine.md feat(rvdna): add npm biomarker engine with risk scoring, streaming, and benchmarks 2026-02-22 15:27:37 +00:00