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Involving Micro and Small Enterprises in the Energy Transition: Evidence from Poland | MDPI

Involving Micro and Small Enterprises in the Energy Transition: Evidence from Poland | MDPI
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Energies
Volume 17
Issue 4
10.3390/en17040847
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AbstractIntroductionEnergy Transition Challenges for BusinessesResearch MethodologyResultsDiscussion and ConclusionsAuthor ContributionsFundingData Availability StatementConflicts of InterestReferencesArticle Metrics
Article
11 February 2024
Involving Micro and Small Enterprises in the Energy Transition: Evidence from Poland
Tomasz Bernat1
,
Sylwia Flaszewska2
,
Renata Lisowska3,*
and
Katarzyna Szymańska2
1
Economics Department, Institute of Economics and Finance, University of Szczecin, 64 Mickiewicza Street, 71-101 Szczecin, Poland
2
Division of Strategic Management, Institute of Management, Faculty of Organization and Management, Lodz University of Technology, 221 Wólczańska Street, 93-005 Lodz, Poland
3
Department of Entrepreneurship and Industrial Policy, Faculty of Management, University of Lodz, 22/26 Matejki Street, 90-237 Lodz, Poland
*
Author to whom correspondence should be addressed.
Energies2024, 17(4), 847;https://doi.org/10.3390/en17040847
This article belongs to the Special Issue Transition of the Energy Systems and the Development of Urban Functional Areas
Version Notes
Order Reprints
Abstract
The energy transition is one of humanity’s most significant challenges. All micro, small, medium, and large enterprises will have to face it, and some are already making progress. This paper focuses on the involvement of the smallest actors in the energy transition. Micro and small enterprises comprise the largest part of the economy and significantly impact its development. Concerning the broad scope of their activities, these entities are characterized by a specific owner–manager relationship. This means that the final decision is influenced by business objectives, the manager’s approach, their awareness of change, and personal and other factors. Based on the analysis of data from 400 companies, it was found that the involvement of micro and small enterprises in the energy transition is related to their market and financial success.
Keywords:
energy transition; micro and small enterprises; energy efficiency; involvement in the energy transition; market and financial results
1. Introduction
Transformation is a long-term change process resulting from economic, social, technological, institutional and/or environmental development. This process also involves energy systems, which, as we know, are not static. Energy transition is a complex and difficult process to describe [1,2,3]. It is expected to contribute to the goals within the realm of sustainable development and the European Green Deal. It will only be possible through the industry’s commitment to actions for a more sustainable economy [4,5,6].
Innovative solutions must be promoted to move smoothly through this process, and governments and companies must invest in technologies based on renewable energy sources. For these activities to be effective, all organizations must participate, including those in the micro and small business sectors [7]. Promoting these processes from the viewpoint of micro and small-sized companies indicates the necessity of adopting a broad perspective on external conditions for developing activities mainly related to the transfer and financing of technological solutions [8]. To strengthen their position in the market and increase the scope of energy transition, the indicated enterprises often have to seek assistance from external sources. Researchers point to the economic benefits of efforts to transition energy. They suggest that the digitization and efficiency of energy consumption activities have an increasing impact on the market and financial performance of pre-enterprises. This is associated with a reasonably fast payback period, which for small projects is only about 3 to 5 years [9]. From an economic perspective, environmental effects are significant. The economic cost–benefit relationship focuses on the growth model associated with maximizing production or service delivery with less energy and resource consumption. Such a value-based approach leads to currently relevant considerations about the purpose of trade and the nature of what is simultaneously beneficial to the business development of the environment in which it operates. Such activities, supported by a broad range of tools and applications, will increase the potential of micro and small businesses to make a genuine and lasting difference in reducing their impact on their part of the environment [10,11].
In light of this, a vital factor in determining the development of businesses in line with the energy transition is collaborating with the environment of these entities. In addition to external adaptation, the internal dimension of the environment of a given enterprise is also crucial in the literature. Under the complete or potential control of a given entity includes various resources used in the management process (i.e., financial, human, physical, and information) that support the development of energy transition [4,12]. It is, therefore, necessary to strive to build open relations between different sectors to support activities aimed at energy transformation. Strong promotion of energy investments for micro and small businesses will arouse the involvement of their owners in these ventures.
Respecting features such as flexibility, entrepreneurship, and innovation is key to implementing environmental programs and increasing the competitiveness of enterprises [13,14].
Therefore, promoting energy transition in micro and small companies is a direction that builds a new quality of their functioning in the market. Therefore, both the role and tasks of the entrepreneur themself are changing. You should also be aware that in crises, these conditions may become critical barriers that have a negative impact on energy transition [15,16,17].
Taking into account that micro and small entities are the most significant part of the economy, have a great influence on its development, and look at the wide scale of their activities, a specific owner–manager relationship distinguishes these entities. This means that business goals influence the final decision making process, the manager’s approach, their awareness of changes, and personal and other factors. Therefore, the area of energy transition for micro and small businesses should be intensively studied by researchers. Polish and foreign researchers have already studied the relationship between the management process, energy transition, and sustainability [18,19,20]. Although discussion of the energy transition touches on financial and market issues and effects [20] more often in large companies, it rarely refers to micro and small companies. The discussion in this area is legitimate because it is essential for realizing environmental goals to develop energy t


CDD Conserved Protein Domain Family: PRK08243

CDD Conserved Protein Domain Family: PRK08243
Conserved Protein Domain Family
PRK08243
Entrez CDD Structure Protein Help
?
PRK08243: PRK08243
Download alignment
4-hydroxybenzoate 3-monooxygenase; Validated
Links
?
Source: PRK
Taxonomy: Bacteria
Protein: Representatives
Specific Protein
Related Protein
Related Structure
Architectures
Superfamily: cl21454
Statistics
?
PSSM-Id: 236198
Aligned: 164 rows
Threshold Bit Score: 488.539
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Download Cn3D
Sequence Alignment
include consensus sequence ?
Format: Hypertext Plain Text mFasta Compact Hypertext Compact Text Row Display: Color Bits: 0.5 bit 1.0 bit 1.5 bit 2.0 bit 2.5 bit 3.0 bit 3.5 bit 4.0 bit Identity Type Selection: top listed sequences the most diverse members

109900192   4 VKTKVAIIGAGPSGLLLGQLLAKQGIDNIIVERVSGEYVLGRIRAGILEQGLVDLLREANVNERMDGEGHVHDGFEISYY 83
300713295   6 EETKVAIIGAGVAGLTLATFLQKSGVPCVVLERRNRTYVEVRQRAGVVEARGVEMFERWGLADKLLA-GPVAQTIDYRVN 84
300783217   3 EHTTVVIVGAGVAGLTLGNILLRNGIDCVILEKYGREHVEQRQRAGTIDSRGVRMFREWGLEEVLAHDAPTEVDAGFFLD 82
134100570   4 VRTRVAVVGAGPSGLLLSHLLHTQGIDSVVLERRSREHVESRVRAGMLEQGVADLIRQAGVGARMDREGFVHDGFELRIG 83
21219815   14 RGISVVVVGAGPAGLTVGSILRAAGVGCLVLETATREVVEHRPRAGVIEEWAVRGLARRGLARTLLERAQAHTECEFRFA 93
290962740  17 MHTTVGIIGGGPAGLLLARLLHNAGIDSVVLERKDRAYVEQRQRAGILEQATVDVLRSAGAGARLDAEGIPHDGIELRYD 96
29830060    1 MRTTVGIIGAGPAGLLLARLLRNAGIDSVVLESRDRAYVERRQRAGILEQGTVDVLRAAGAGERMDREGLRHDGIELRFD 80
256394023   1 MHTTVGIIGAGPAGLLLARLLHQAGVDSVVLEARDREYVEQRQRAGILEQVTVDALRAAGAGERMDREGIVHHGIELRFA 80
256422806  10 EKTQVVIIGAGVSGLTLATFLQKSGVACVIVERRNRAYIEMRQRAGVVEARGVHMFERWGLADKLLG-GPVAQTIDYRVN 88
296270791   2 MRTTVGIVGGGPAGLLLARLLRRSGIDCVVLESRDRAYVEQRQRAGILEQGAADILRECGAGERMDREGLVHDGIELRFA 81

109900192  84 GTPYRIDL--NKLTDGKTVMCYGQTEVTRDLMQA-RETKALTTYYSASDVSLHD------IESAHPTVTF--SQDGVNYT 152
300713295  85 GVGRIFDI---GAEGDAQSRFCTQQMLVNNLLRElIDAMAGDVRFEVADVVITN------EADRRPSVAY--SDAGGHHE 153
300783217  83 GEELPIDF----SADDNDSVFLPQQVLVRNLTDA-FLRAGGDLRFEADSITLEN--------LEHPVVRY------GDNV 143
134100570  84 DRRHRVSL--TGLT-GRTVCMYGQQELVKDLIRA-RTEAAATLHFGVEDVKLHG------LTGDAPVVRC--TIDGEPTE 151
21219815   94 GERYRFGY--TGLT-GRHHFVYPQQFLVTDLVREyADVRGGEIRFGVRDVRLHG------TGSARPAVSYvcPDSGERRV 164
290962740  97 GRAHRVDF--PGLTGGRRVWVYAQTEVVKDLIAL-QLTGGGPLLFEAEVHAVEG------ADTDRPSIRY--THEGREQT 165
29830060   81 RRRHRVDF--PALAGGRAVMVYAQTEVCKDLIAL-QLEEGGPLLFGAEALAVEG------AGTERPRVPF--THEGREDV 149
256394023  81 GRSQRIDF--AVLAGGRGVMVYAQTEMVKDLIAL-HLAHGGPLLFEAGVSSVGAvgavgtADDDRIAVRY--RRDGREQT 155
256422806  89 GVGRVFEIvgDDRIQGRFCT---QQMLVNNLLKElIDGMSGDVRFEVTDVQIKN------EEGVQPEVTY--RYADSEHV 157
296270791  82 RRSHRIDF--PSLTGGRRVMVYAQTEVVKDLIRL-HLEDGTPLLFEATATAITG------IDADRPVIHF--VHEGREKT 150

109900192 153 LECDYIAGCDGFHGVSRKSIPEEKRNEFERVYPFGWLGLLSDTPPVSDELIYCKTERGFALASMRSSSRSRYYLQVPLTD 232
300713295 154 IACDFIVGCDADRGVSRASIPDGILTRYVHEFGYAWMAALVEA-PVTGDPIMAVSDHGFVGQLPRGPQRSRYYLQCALTD 232
300783217 144 VTAGFIAGCDGDRGVSRTAFPAGVLTRYSREYGYAWLSVLAEVPANPSGM--AIHSRGLAGMLPRGPHASRTYLQCALDD 221
134100570 152 ITCDFVAGCDGFHGVSRRSVPASALSVYEHEYPFAWLGVLARMPPVASELVYSAHERGFALYSMRTESLSRLYLQVAPDD 231
21219815  165 VEADFVAGCDGARGVTRASLPAGRVRLARHDYGVGWLALLAEAPPSSDCVVFGMHPRGFAGHMARSPEVTRYYLQCPPGD 244
290962740 166 LTCDYVVGCDGFHGVARDAVPDGVRTTYERTYPYSWLGILADAPPVYDELIYAHSERGFALASMRSPSVSRLYLQVPNGT 245
29830060  150 LECDYVVGCDGFRGVARQAVPAEVSRVFERTYPFGWLGVLADVAPSHDELVYARHERGFALLSMRSPAVSRLYLQVPEGT 229
256394023 156 LTCDWAVGCDGFHGVTKDAVPADLRHTYERTYPYSWLGILADAPPVYDELIYAHSDRGFALASMRSDTVSRLYLQVPNGT 235
256422806 158 LVCDYIVGCDGDRGVSRASIPEGILTKYSHEFGYAWLAALVEAPVTGHPIM-GVSDHGCVAQLPRGPHRSRYYLQCALSD 236
296270791 151 LTCEYVVGCDGFHGITREAIRGAI-TTYEHVYPYSWLGILADVPPSCDELIYAHSERGFALHSMRGRTVSRLYLQVPNGS 229

109900192 233 KVEQWSDERFWDELRKRLP--QEAASNLITGPSLEKSIAPLRSFVCEPMQLGKLFLVGDAAHIVPPTGAKGLNLAASDVS 310
300713295 233 TAEDWPEKRIWDEIRVRLN--D---DTIQNAVVHNIDFVPLRSVVYAPMQYGNLFLAGDAAHMVPPASAKGMNMALYDVD 307
300783217 222 DLAQWPDERVWSELEARFG------RPVASGRIADKRLVPLRNVVHSPMQSGKLHLLGDAAHIVPPMSAKGIHLALFDAE 295
134100570 232 DGSTWPPELIWKELATRLG--PDASEVLRPGPILETSVTRMRGFVAEPMQYGRLFLAGDAAHIVPPTAAKGLNLAVGDVR 309
21219815  245 SPENWPHERVWAELRERLG--AAGAPPLAEGRLIEKRVLDMHSYVVEPMAFGRLFLAGDAAHLTAPIAAKGLNLALHDAF 322
290962740 246 DPGDWSDERIWDELDARLAltANPGWRLKRGPVTSKAVLPMRSHVTEPMRYGRVFLAGDAAHIVPPTGAKGLNLAATDVI 325
29830060  230 DAEAWADDEIWAELERRFE--TDDAWRLERGPITQKSVTPMRGYVHEPMRHGRLFLAGDAAHIVPPTGAKGLNLAVGDVV 307
256394023 236 DPAAWSDDRIWDELDRRFAtrADPGWKLTRGPITAKSVLPMRSHVTEPMRHGRVLLAGDTAHIVPPTGAKGLNLATGDVI 315
256422806 237 GAQDWPDDRLWNEIRLRLQ--D---ETIQNVKVHDKFFVPLRSVVYAPMQYRHLYLAGDAAHLVPPASAKGMNLALFDVD 311
296270791 230 GVDEWPDDRIWDELDARFA--IDGDWKLERGPITSKAVLPMRSFVTEPMRHRRVFLAGDAAHIVPPTGAKGLNLALGDVA 307

109900192 311 TLYRLLTKEYNEGATNASQQYSEIALRRVWHAERFSWWMSNMLHEFtdcgGDANNMDnktfERFMASELDFYLSHQEGQQ 390
300713295 308 VLAQALLDAVRNQDRRTLDSYTDTCLPRIWNYQDFAVWMTDTMHDAsn-pAQQGTFR----QMTARSRLNNLFASPAAAR 382
300783217 296 VFARGVIRQAKENDPSLLDSYSETCLSHVWNYQAFAAWITDIMHDA-----GDASYAgefrKRVARAELERQFTSAAAGR 370
134100570 310 TLAQAFARWYSSGDRGPLDEYSATCLPAVWRAQEFSAAMTWLLHRP----ADSTGFT----ERLRRSRLENLVSSRAAAT 381
21219815  323 LLGDGLVAALTKGDDSALAGYSDACLARVWDYQEFSQWLAEMYHGT----ASGDPYR----AGAALARLRRLFSSPAAAA 394
290962740 326 VLARAFARLRETGSTELLDAYSDTCLRRVWRAEHFSYFMTTTLHAD----PDQSPFE----TRLQLAQLDRVATSRHAAA 397
29830060  308 TFARALTHLKETGSGERLDAYSATCLRRVWQAERFSYDMTTLLHRP----PAATPFE----ERVQLARLERITSSRAAEA 379
256394023 316 ILARALAHWKETGSAELLDAYSDTCLERVWRAEHFSYFMTTTLHVD----PDQSAFD----TRLQLSQLARIAASPHAAA 387
256422806 312 ILAQGLLQALQHNDHTALLNYSDTCLPHIWKYQEFAVWMTDMMHDAgd-pTQHGTFY----QMIARARLDNLFSSPIAAH 386
296270791 308 VLARAFIYLHTTGSSELLDAYSDTRLRRVWRAEHFSYFMTTTLHLG----PEQTPFQ----TRLQLAQLERIVTSRAAAA 379

109900192 391 VIATQYVGMPY 401
300713295 383 LHGEYQRGTN- 392
300783217 371 LFAEFMAGVA- 380
134100570 382 EFAENYVGVSR 392
21219815  395 EFAERYLGVRT 405
290962740 398 ELAENYTGLSL 408
29830060  380 DLAEGYTGSPW 390
256394023 388 ELAQNYVGIPI 398
256422806 387 QHSEYQRGML- 396
296270791 380 ELAENYTGLPL 390
Citing CDD
Jiyao W et al.(2023). "The conserved domain database in 2023.", Nucleic Acids Res. 51(D1):D384-D388.
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Dok je on zatvoren u sobi “žvrljao” po papiru, ona je prodavala sve što je imala da bi preživali: 13 godina je čekala da je oženi, a ovim rečima je osvojio
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April 27, 2025
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U današnjem članku želim da vam ispričam priču koja se dogodila pre mnogo godina, ali koja i dalje inspiriše i dirnuti svakog ko je pročita.
Ova priča govori o ljubavi, strpljenju, poverenju i verovanju u snove, a glavni akteri su jedan od najvećih pisaca 20. veka i žena koja je u svakom smislu bila njegova podrška, njegova inspiracija, a i kamen-temeljac u životu.
Imala je samo 13 godina kada joj je rekao: „Budi moja žena.“ Bilo je to na plesnom podijumu, dok je mršavi dečak sa iskrom u očima prišao i rekao: „Upravo sam shvatio da su sve moje pesme o tebi. Udaj se za mene!“ Njegov pogled bio je pun strasti i nade, a reči su bile iskrene, iako nisu bile ozbiljno shvaćene. Devojka, mlada i još uvek nedovoljno odrasla da razmišlja o braku, podigla je pogled prema njemu i mirno odgovorila: „U redu. Ali pusti me da prvo završim školu.“ Tada, na tom plesnom podijumu, započela je priča koja je kasnije postala legendarna.
On je bio Gabrijel Garsija Markes, a ona je bila Mercedes. Dugo su čekali, ali ljubav koju su gajili bila je nepokolebljiva. Njihova veza nije bila samo priča o romantičnom angažmanu, već priča o podršci i poverenju, o tome kako je ljubav, čak i kada nije zvanično ozvaničena, najčistiji oblik zajedništva. Venčali su se tek 13 godina kasnije. Iako nisu bili zvanično vereni, Markes je kasnije rekao: „Nismo čekali venčanje, samo smo strpljivo čekali ono što je trebalo da bude.“
Dok je Gabrijel bio zatvoren u svojoj sobi, pišući remek-delo „Sto godina samoće“, Mercedes je bila ta koja je nosila ceo njihov svet. Njena vernost, njeno poverenje u njegov talenat, i njena posvećenost porodici nisu bile samo znakovi ljubavi, već i njene nepopustljive nade da će on jednog dana ostvariti sve što je zamislio. Verovala je u njega čak i kada su okolnosti bile teške, kada su novci bili ograničeni, a snovi su delovali daleko. Bez obzira na sve, nikada nije sumnjala da je njen muž genije, i nikada nije napustila njegov san.
Kada je rukopis njegovog dela bio gotov, nisu imali dovoljno novca da ga pošalju. Mercedes je tada učinila nešto što će se kasnije činiti kao herojski potez. Prodala je svoje poslednje stvari, kao što su fen za kosu i blender, da bi poslala rukopis na adresu izdavača. Ova žrtva, u kojoj se prepoznao njen duboki ljubavni odnos prema Markesu, pokazala je koliko je ona verovala u njegovu misiju i njegov talenat. Nije se žalila, niti se kajala, jer je znala da je to bio korak ka nečemu većem od nje, nešto što je bilo daleko od trenutnih problema i nesigurnosti.
Mesecima kasnije, svet je saznao ime Gabrijela Garsije Markesa. Njegovo delo, roman „Sto godina samoće“, zauvek je promenio književnost. Ovaj roman nije samo postao najvažniji deo književnog kanona Latinske Amerike, već je doneo Markesu i Nobelovu nagradu za književnost. Bez obzira na njegov kasniji uspeh, važno je shvatiti da bi bez Mercedesine podrške, žrtve i vere u njega, Markes možda nikada ne bi dostigao svoj potencijal. Njegov uspeh nije bio samo njegov, već i njihov, jer je bio rezultat godina zajedničke borbe, ljubavi i uzajamnog poštovanja.
Ova priča je snažna podsećanja na to kako ljubav i podrška između dvoje ljudi mogu stvoriti nevjerovatne stvari. Gabrijel Garsija Markes postao je svetli primer toga kako ljubav i vera u partnera mogu oblikovati ne samo njihove živote, već i svet oko njih. Mercedes je bila ta koja je tiho, ali neizmerno značajno, doprinosila njegovom uspehu, iako nikada nije tražila priznanje. Njena ljubav bila je čista, nepokolebljiva, i u tom njenom verovanju u njega leži ključ svega što su postigli zajedno.
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Frontiers | Extremophilic Bacterium Halomonas desertis G11 as a Cell Factory for Poly-3-Hydroxybutyrate-co-3-Hydroxyvalerate Copolymer’s Production

Frontiers | Extremophilic Bacterium Halomonas desertis G11 as a Cell Factory for Poly-3-Hydroxybutyrate-co-3-Hydroxyvalerate Copolymer’s Production
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ORIGINAL RESEARCH article
Front. Bioeng. Biotechnol., 23 May 2022
Sec. Bioprocess Engineering
Volume 10 - 2022 | https://doi.org/10.3389/fbioe.2022.878843
This article is part of the Research TopicCurrent Challenges in Biodegradable Polyhydroxyalkanoates: From The Cradle To The GraveView all 7 articles
Extremophilic Bacterium Halomonas desertis G11 as a Cell Factory for Poly-3-Hydroxybutyrate-co-3-Hydroxyvalerate Copolymer’s Production
Khouloud Hammami1 Yasmine Souissi1,2 Amal Souii1 Awatef Ouertani1 Darine El-Hidri1 Marwa Jabberi1 Habib Chouchane1 Amor Mosbah1 Ahmed Slaheddine Masmoudi1 Ameur Cherif1 Mohamed Neifar1,3*
1BVBGR-LR11ES31, Higher Institute of Biotechnology of Sidi Thabet (ISBST), University of Manouba, Ariana, Tunisia
2Department of Engineering, German University of Technology in Oman, Muscat, Oman
3APVA-LR16ES20, National School of Engineers of Sfax (ENIS), University of Sfax, Sfax, Tunisia
Microbial polyhydroxyalkanoates (PHA) are biodegradable and biocompatible bio-based polyesters, which are used in various applications including packaging, medical and coating materials. In this study, an extremophilic hydrocarbonoclastic bacterium, previously isolated from saline sediment in the Tunisian desert, has been investigated for PHA production. The accumulation of intracellular PHA granules in Halomonas desertis G11 was detected by Nile blue A staining of the colonies. To achieve maximum PHA yield by the strain G11, the culture conditions were optimized through response surface methodology (RSM) employing a Box-Behnken Design (BBD) with three independent variables, namely, substrate concentration (1–5%), inoculum size (1–5%) and incubation time (5–15 days). Under optimized conditions, G11 strain produced 1.5 g/L (68% of DCW) of PHA using glycerol as a substrate. Application of NMR (1H and 13C) and FTIR spectroscopies showed that H. desertis accumulated PHA is a poly-3-hydroxybutyrate-co-3-hydroxyvalerate (PHBV). The genome analysis revealed the presence of typical structural genes involved in PHBV metabolism including phaA, phaB, phaC, phaP, phaZ, and phaR, coding for acetyl-CoA acetyltransferase, acetoacetyl-CoA reductase, class I polyhydroxyalkanoates synthases, phasin, polyhydroxyalkanoates depolymerase and polyhydroxyalkanoates synthesis repressor, respectively. Glycerol can be metabolized to 1) acetyl-CoA through the glycolysis pathway and subsequently converted to the 3HB monomer, and 2) to propionyl-CoA via the threonine biosynthetic pathway and subsequently converted to the 3HV monomer. In silico analysis of PhaC1 from H. desertis G11 indicated that this enzyme belongs to Class I PHA synthase family with a “lipase box”-like sequence (SYCVG). All these characteristics make the extremophilic bacterium H. desertis G11 a promising cell factory for the conversion of bio-renewable glycerol to high-value PHBV.
Introduction
Fossil fuel-based plastics play a crucial role in modern lifestyle (Chae and An, 2018). Approximately 400 million tons of plastic were produced globally in 2018. More than 10 million metric tons of plastic ended up into the oceans during 2018 alone. An estimated 13 billion tons of plastic waste will reach the environment by 2050 in the absence of any improvements in current plastic waste management practices (Shams et al., 2021). Synthetic plastics have significant negative impacts on ecosystems, biota, environment, economy, and human health (Sharma and Chatterjee, 2017). As a result, there is a growing demand for bioplastics such as polyhydroxyalkanoates (PHA), polylactic acid, biopolyamide, biopolyethylene and biopolypropylene that provide new solutions in terms of life cycle and raw materials (Akinwumi et al., 2019). The conversion of biowastes to PHAs is considered as a possible eco-friendly alternative to petro-plastics and are currently gaining a lot of interest in the field of industrial applications and waste management (Kourmentza et al., 2017; Patel et al., 2021). Global bioplastic production has increased from 2.1 metric tons in 2020 to about 2.4 metric tons in 2022 (Dubey and Mishra, 2021) and the market opportunity for PHA bioplastic could reach US$100 million by 2024 (Surendran et al., 2020).
PHA are linear polyesters that consist of hydroxy fatty acids and are synthesized by a wide range of different Gram-positive and Gram-negative bacteria, as well as in some haloarchaeal species (Bugnicourt et al., 2014; Han et al., 2015; Kalia et al., 2021). Among the PHA producing microorganisms, the most-studied were Pseudomonas oleovorans, P. aeruginosa and P. putida, Bacillus megaterium, B. cere


Frontiers | A study on land compactness of urban agglomeration-example from Beijing-Tianjin-Hebei

Frontiers | A study on land compactness of urban agglomeration-example from Beijing-Tianjin-Hebei
Frontiers in Environmental Science
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Drylands
Ecosystem Restoration
Environmental Citizen Science
Environmental Economics and Management
Environmental Informatics and Remote Sensing
Environmental Policy and Governance
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Interdisciplinary Climate Studies
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ORIGINAL RESEARCH article
Front. Environ. Sci., 19 August 2022
Sec. Land Use Dynamics
Volume 10 - 2022 | https://doi.org/10.3389/fenvs.2022.969562
This article is part of the Research TopicLand Governance, Integrated Socio-Ecosystem and Sustainable DevelopmentView all 33 articles
A study on land compactness of urban agglomeration-example from Beijing-Tianjin-Hebei
Huiying Wang1 Huimin Wang2* Xuehan Xiong3
1School of Government, University of International Business and Economics, Beijing, China
2Department of Aviation Economics and Management, Beijing Institute of Economics and Management, Beijing, China
3Development Holdings Co., Ltd., Hainan, China
Compactness, intensity, efficiency and greenness are becoming the goals of regional governance in China. This study, based on the compact development theory, takes the urban agglomeration of Jingjinji as the research object, uses the composite index to construct a compactness index system based on production-living-ecological space and adopts entropy method to measure and analyze the degree of compactness. The results show that there is an obvious internal differentiation in Jingjinji, and the overall situation is not compact. Composed of production, living and ecological spaces, the compactness of the territorial space differs significantly. Production space is of the highest degree compactness, followed by living space and the lowest is ecological space. By comparing each index, compactness degrees of economic factors and municipal production facilities are better than those of the production land and transportation. Compactness degrees of Social factors of living space are more developed than those of residential land and public services. The overall compactness degree of the ecological space is the lowest, but the degrees of compactness are relatively balanced and there are small differences. The compactness degree of the green land is slightly lower than that of pollution treatment.
1 Introduction
Starting from “14th Five-Year Plan”, China focused on the overall and systematic governance of the entire territorial space, classified into production, living and ecological spaces (PLES). Meanwhile, the urban agglomeration has become the main geographical unit and spatial development pattern in China due to significant aggregation of population and economic functions. However, the main problem has been that regional development is unbalanced, uncoordinated and incompact in some urban agglomerations, especially in the Beijing-Tianjin-Hebei region (also known as Jingjinji).
From the perspective of PLES in the urban agglomeration of Jingjinji, the development of production space is seriously differentiated, and high efficiency has not yet been achieved in every city. The provision of living space is not diverse and abundant, so high-quality development has not yet been achieved. In addition, the ecological space is not adequately protected by the Regulations for the Implementation of the Land Administration Law, the policy that should scientifically control territorial planning.
Above all, a series of economic, social and ecological problems still exist in the Jingjinji urban agglomeration. Therefore, how to formulate a governance plan in accordance with local conditions and promote heterogeneous regions to exploit comparative advantages and achieve highly efficient and qualified development, has become an inherent requirement for the Jingjinji urban agglomeration in order to further optimize territorial space.
2 Literature review
In the context of spatial governance and planning, academic research on land governance has also achieved new progress. Since the conservation and use of land resources is one of the important goals of spatial governance, the compact development theory related to urban development has been gradually adopted in spatial governance research. The compact development theory originates from the “compact city” proposed by European and American countries to achieve sustainable development.
Danziger and Satty 1973) were the first to present the compact city theory in the context of achieving sustainable development (Dantizing and Satty, 1973). They believed that a compact ci


Contributor: Spisak, Shelley (Editor) - Reports of the Surgeon General - Profiles in Science Search Results

Contributor: Spisak, Shelley (Editor) - Reports of the Surgeon General - Profiles in Science Search Results
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1. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (pages 76-100)
Creator:
National Center for Education in Maternal and Child Health (U.S.)
United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
United States. Public Health Service. Office of the Surgeon General
Date:
1991
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National Center for Education in Maternal and Child Health (U.S.)
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Workshops (seminars)
2. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (pages 51-75)
Creator:
National Center for Education in Maternal and Child Health (U.S.)
United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
United States. Public Health Service. Office of the Surgeon General
Date:
1991
Publisher:
National Center for Education in Maternal and Child Health (U.S.)
Genre:
Official reports
Excerpts
Workshops (seminars)
3. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (pages 26-50)
Creator:
National Center for Education in Maternal and Child Health (U.S.)
United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
United States. Public Health Service. Office of the Surgeon General
Date:
1991
Publisher:
National Center for Education in Maternal and Child Health (U.S.)
Genre:
Official reports
Excerpts
Workshops (seminars)
4. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (pages 101-116)
Creator:
National Center for Education in Maternal and Child Health (U.S.)
United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
United States. Public Health Service. Office of the Surgeon General
Date:
1991
Publisher:
National Center for Education in Maternal and Child Health (U.S.)
Genre:
Official reports
Excerpts
Workshops (seminars)
5. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (pages 1-25)
Creator:
National Center for Education in Maternal and Child Health (U.S.)
United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
United States. Public Health Service. Office of the Surgeon General
Date:
1991
Publisher:
National Center for Education in Maternal and Child Health (U.S.)
Genre:
Official reports
Excerpts
Workshops (seminars)
6. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (Title Page and Introductory Material)
Creator:
National Center for Education in Maternal and Child Health (U.S.)
United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
United States. Public Health Service. Office of the Surgeon General
Date:
1991
Publisher:
National Center for Education in Maternal and Child Health (U.S.)
Genre:
Official reports
Excerpts
Workshops (seminars)
7. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation (Index)
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National Center for Education in Maternal and Child Health (U.S.)
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8. Second Followup Report: The Surgeon General's Workshop on Breastfeeding and Human Lactation
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United States. Public Health Service. Health Resources and Services Administration. Maternal and Child Health Bureau
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Cáncer de mama - Médicos y departamentos - Mayo Clinic

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Reconstrucción de los senos con implantes , Cirugía reconstructiva, Reparación de fractura facial, Transferencia de tej...ido adiposo, Cirugía plástica de los senos, cirugía de feminización facial, cirugía para reasignación de sexo, Reconstrucción de los senos, Cirugía microvascular, reconstrucción facial , cirugía oncoplástica conservadora de mamas, colgajo libre, reconstrucción de la pared abdominal, Cuidado de la herida, reparación de fístula rectovaginal, Cambio del implante mamario, reconstrucción microvascular , Cirugía de mama, Cirugía con colgajo, Cáncer de mama, angiosarcoma de mama, Nariz quebrada, Fístula rectovaginal, Fractura, mandíbula quebrada, Fractura orbital, laceración facial, fractura facial, Herida, lesión facial
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NIH VideoCast - IIG Seminar - Multimodal decoding of liver regeneration and repair

NIH VideoCast - IIG Seminar - Multimodal decoding of liver regeneration and repair
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Frontiers | FEV Maintains Homing and Expansion by Activating ITGA4 Transcription in Primary and Relapsed AML

Frontiers | FEV Maintains Homing and Expansion by Activating ITGA4 Transcription in Primary and Relapsed AML
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ORIGINAL RESEARCH article
Front. Oncol., 07 July 2022
Sec. Hematologic Malignancies
Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.890346
This article is part of the Research TopicNew Emerging Functions of Transcription Factors and RNA-Binding Proteins in the Development of Hematological MalignanciesView all 7 articles
FEV Maintains Homing and Expansion by Activating ITGA4 Transcription in Primary and Relapsed AML
Jubin Zhang1,2† Lijuan Qi1,2† Tanzhen Wang1,2† Jingnan An1,2 Biqi Zhou1,2 Yanglan Fang1,2 Yujie Liu1,2 Meng Shan1,2 Dengli Hong3 Depei Wu1,2* Yang Xu1,2* Tianhui Liu1,2*
1National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
2Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
3Key Laboratory of Cell Differentiation and Apoptosis of Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China
Acute myeloid leukemia (AML) is an aggressive hematological malignancy that recurs in approximately 50% of cases. Elevated homing and uncontrolled expansion are characteristics of AML cells. Here, we identified that Fifth Ewing Variant (FEV) regulates the homing and expansion of AML cells. We found that FEV was re-expressed in 30% of primary AML samples and in almost all relapsed AML samples, and FEV expression levels were significantly higher in relapsed samples compared to primary samples. Interference of FEV expression in AML cell lines delayed leukemic progression and suppressed homing and proliferation. Moreover, FEV directly activated integrin subunit alpha 4 (ITGA4) transcription in a dose-dependent manner. Inhibition of integrin α4 activity with natalizumab (NZM) reduced the migration and colony-forming abilities of blasts and leukemic-initiating cells (LICs) in both primary and relapsed AML. Thus, our study suggested that FEV maintains the homing and expansion of AML cells by activating ITGA4 transcription and that targeting ITGA4 inhibits the colony-forming and migration capacities of blasts and LICs. Thus, these findings suggested that the FEV-ITGA4 axis may be a therapeutic target for both primary and relapsed AML.
Introduction
Acute myeloid leukemia (AML) is an aggressive hematological malignancy in which immature cells accumulate and expand uncontrollably. Nearly 50% of patients relapse after induction chemotherapy (1, 2). Although new approaches have improved the prognosis of some patients, the majority of primary and relapsed AML patients still lack effective treatment (1–4). Therefore, there is an urgent need for novel targets or drugs to improve the outcomes of these patients.
Enhanced homing and migration abilities are features of AML cells, which rapidly home to bone marrow (BM) and hijack the normal hematopoietic niche to aid extensive expansion of leukemic initiating cells (LICs) (5–7). Cell-to-cell or cell-to-matrix interactions mediated by C-X-C Motif Chemokine Receptor 4 (CXCR4)- C-X-C Motif Chemokine Ligand 12 (CXCL12), integrins and CD44 signaling pathways have been reported to contribute to the homing of leukemic cells to the BM microenvironment (5–11). However, the upstream mechanism that activates the pathways of VLA-4 remains unknown. Here, we identified that fifth Ewing variant (FEV) regulates integrin signaling.
FEV (also known as PET1 in mammals) is an E26 transformation-specific transcripti


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東南亞地區登革熱疫情嚴峻，疾管署呼籲國人前往高風險地區務必做好防蚊措施 - Taiwan Centers for Disease Control

東南亞地區登革熱疫情嚴峻，疾管署呼籲國人前往高風險地區務必做好防蚊措施 - Taiwan Centers for Disease Control
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東南亞地區登革熱疫情嚴峻，疾管署呼籲國人前往高風險地區務必做好防蚊措施
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依據疾病管制署疫情監測資料，目前東南亞數國如新加坡、馬來西亞及泰國等登革熱疫情頻傳，其中新加坡截至第6週累計通報2,162例登革熱病例，為去(102)年同期的1.5倍，近5年同期平均的3.7倍；馬來西亞登革熱疫情，每週新增約2千例的幅度持續增加，今年至2月初已累計通報11,870例，為去年同期的3.8倍。疾管署呼籲國人，前往登革熱高風險地區務必做好防蚊措施，避免感染登革熱。
今年截至2月18日，國內共累計21例境外移入登革熱病例，感染來源分別為印尼9例、馬來西亞6例、菲律賓3例、新加坡2例及柬埔寨1例。去年同期則有24例，主要來自印尼（8例）及泰國（6例）。
疾管署提醒，國人前往登革熱高風險地區旅遊、探親及經商，應確實做好個人防蚊措施，於身體裸露處使用經衛生福利部核可的防蚊藥劑，並盡量穿著淺色長袖衣褲，以避免遭病媒蚊叮咬。旅遊期間或回國後如出現發燒、頭痛、噁心、嘔吐、肌痛、出疹及關節痛等症狀，應儘速就醫，並告知醫師旅遊史，以利及早診斷治療。
有關登革熱最新疫情及各項資訊，請參閱疾病管制署全球資訊網(http://www.cdc.gov.tw) 或撥打國內免付費防疫專線1922洽詢，如話機無法撥打簡碼電話號碼，請改撥0800-001922防疫專線。
PublishTime 2014/2/21
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Roberts JD - Search Results - PubMed

Roberts JD - Search Results - PubMed
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1
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Medical marijuana certification for patients with sickle cell disease: a report of a single center experience.
Curtis SA, Lew D, Spodick J, Hendrickson JE, Minniti CP, Roberts JD. Curtis SA, et al. Among authors: roberts jd. Blood Adv. 2020 Aug 25;4(16):3814-3821. doi: 10.1182/bloodadvances.2020002325. Blood Adv. 2020. PMID: 32790846 Free PMC article.
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Comorbidity, Pain, Utilization, and Psychosocial Outcomes in Older versus Younger Sickle Cell Adults: The PiSCES Project.
McClish DK, Smith WR, Levenson JL, Aisiku IP, Roberts JD, Roseff SD, Bovbjerg VE. McClish DK, et al. Among authors: roberts jd. Biomed Res Int. 2017;2017:4070547. doi: 10.1155/2017/4070547. Epub 2017 Mar 28. Biomed Res Int. 2017. PMID: 28459058 Free PMC article.
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Marijuana Use in Adults Living with Sickle Cell Disease.
Roberts JD, Spodick J, Cole J, Bozzo J, Curtis S, Forray A. Roberts JD, et al. Cannabis Cannabinoid Res. 2018 Jul 1;3(1):162-165. doi: 10.1089/can.2018.0001. eCollection 2018. Cannabis Cannabinoid Res. 2018. PMID: 30014039 Free PMC article.
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Red blood cell alloimmunization is associated with lower expression of FcγR1 on monocyte subsets in patients with sickle cell disease.
Balbuena-Merle R, Curtis SA, Devine L, Gibb DR, Karafin MS, Luckey CJ, Tormey CA, Siddon AJ, Roberts JD, Hendrickson JE. Balbuena-Merle R, et al. Among authors: roberts jd. Transfusion. 2019 Oct;59(10):3219-3227. doi: 10.1111/trf.15463. Epub 2019 Jul 29. Transfusion. 2019. PMID: 31355970 Free PMC article.
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Utilization, financial outcomes and stakeholder perspectives of a re-organized adult sickle cell program.
Rousseau R, Weisberg DF, Gorero J, Parwani V, Bozzo J, Kenyon K, Smith C, Cole J, Curtis S, Forray A, Roberts JD. Rousseau R, et al. Among authors: roberts jd. PLoS One. 2020 Jul 24;15(7):e0236360. doi: 10.1371/journal.pone.0236360. eCollection 2020. PLoS One. 2020. PMID: 32706825 Free PMC article.
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Building access to care in adult sickle cell disease: defining models of care, essential components, and economic aspects.
Kanter J, Smith WR, Desai PC, Treadwell M, Andemariam B, Little J, Nugent D, Claster S, Manwani DG, Baker J, Strouse JJ, Osunkwo I, Stewart RW, King A, Shook LM, Roberts JD, Lanzkron S. Kanter J, et al. Among authors: roberts jd. Blood Adv. 2020 Aug 25;4(16):3804-3813. doi: 10.1182/bloodadvances.2020001743. Blood Adv. 2020. PMID: 32785684 Free PMC article.
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Urinary cannabinoid mass spectrometry profiles differentiate dronabinol from cannabis use.
Koch CD, Xu L, Curtis SA, Roberts JD, Bunch DR, El-Khoury JM. Koch CD, et al. Among authors: roberts jd. Clin Chim Acta. 2020 Nov;510:515-521. doi: 10.1016/j.cca.2020.08.014. Epub 2020 Aug 12. Clin Chim Acta. 2020. PMID: 32795544
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Daily Cannabis Users with Sickle Cell Disease Show Fewer Admissions than Others with Similar Pain Complaints.
Curtis SA, Brandow AM, DeVeaux M, Zeltermam D, Devine L, Roberts JD. Curtis SA, et al. Among authors: roberts jd. Cannabis Cannabinoid Res. 2020 Sep 2;5(3):255-262. doi: 10.1089/can.2019.0036. eCollection 2020. Cannabis Cannabinoid Res. 2020. PMID: 32923662 Free PMC article.
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Non-crisis related pain occurs in adult patients with sickle cell disease despite chronic red blood cell exchange transfusion therapy.
Curtis SA, Raisa BM, Roberts JD, Hendrickson JE, Starrels J, Lesley D, Michelle D, Daniel Z, Brandow AM. Curtis SA, et al. Among authors: roberts jd. Transfus Apher Sci. 2022 Apr;61(2):103304. doi: 10.1016/j.transci.2021.103304. Epub 2021 Oct 30. Transfus Apher Sci. 2022. PMID: 34782244 Free PMC article.
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Purification, characterization and protective effects on UVB-induced photoaging in zebrafish of Pleurotus citrinopileatus polysaccharide PCP-2

Purification, characterization and protective effects on UVB-induced photoaging in zebrafish of Pleurotus citrinopileatus polysaccharide PCP-2
Purification, characterization and protective effects on UVB-induced photoaging in zebrafish of Pleurotus citrinopileatus polysaccharide PCP-2
J Sci Food Agric. 2025 Aug 15;105(10):5246-5257. doi: 10.1002/jsfa.14247. Epub 2025 Mar 28.
Authors
Yan-Xia Li 1 , He Ma 1 , Le Shi 1 , Zhong-Fei Zhang 1 , Yu-Meng Wu 1 , Chao Yan 1 2 , Yan Chen 1 2 , Yong-Ming Lu 1 2
Affiliations
1 School of Life Sciences, Anhui University, Hefei, People's Republic of China.
2 Key Laboratory of Ecological Engineering and Biotechnology of Anhui Province and Anhui Key Laboratory of Modern Biomanufacturing, Hefei, People's Republic of China.
PMID: 40156221
DOI: 10.1002/jsfa.14247
Abstract
Background: Polysaccharides from Pleurotus citrinopileatus exhibit diverse bioactivities, yet their efficacy against ultraviolet B (UVB)-induced photoaging remains unexplored. This study aimed to purify and characterize a specific PCP and assess its protective effects using a UVB-induced zebrafish model.
Results: A polysaccharide, designated as PCP-2, was isolated from P. citrinopileatus through hot-water extraction, ultrafiltration and chromatography. PCP-2 is a galactoglucan with a molecular weight of 1.52 × 106 Da, predominantly composed of 1,4-linked glucopyranosyl and 1,4,6-linked galactopyranosyl residues. In UVB-exposed zebrafish, PCP-2 administration resulted in a significant reduction of reactive oxygen species and malondialdehyde levels, alongside enhanced activities of antioxidant enzymes, including superoxide dismutase, catalase and glutathione peroxidase. Additionally, PCP-2 inhibited apoptosis by upregulating Bcl-2 expression and downregulating caspase-3. It also attenuated cellular senescence, as indicated by decreased β-galactosidase activity and increased telomerase activity. Moreover, PCP-2 promoted the synthesis of type I and III collagen by suppressing matrix metalloproteinases MMP-1 and MMP-3 and reduced melanin production through the downregulation of tyrosinase expression. Mechanistic studies suggested that these protective effects are mediated via activation of the Nrf2/HO-1 signaling pathway.
Conclusion: PCP-2 from P. citrinopileatus effectively mitigates UVB-induced photoaging, primarily by activating the Nrf2/HO-1 pathway. These findings suggest PCP-2's potential as an anti-photoaging agent in both food and pharmaceutical industries. © 2025 Society of Chemical Industry.
Keywords: Pleurotus citrinopileatus polysaccharide; anti‐photoaging; zebrafish.
© 2025 Society of Chemical Industry.
MeSH terms
Animals
Antioxidants / chemistry
Antioxidants / isolation & purification
Antioxidants / pharmacology
Apoptosis / drug effects
Apoptosis / radiation effects
Caspase 3 / genetics
Caspase 3 / metabolism
Catalase / genetics
Catalase / metabolism
Glutathione Peroxidase / genetics
Glutathione Peroxidase / metabolism
Humans
Malondialdehyde / metabolism
Matrix Metalloproteinase 1 / genetics
Matrix Metalloproteinase 1 / metabolism
Pleurotus* / chemistry
Polysaccharides* / administration & dosage
Polysaccharides* / chemistry
Polysaccharides* / isolation & purification
Polysaccharides* / pharmacology
Protective Agents* / chemistry
Protective Agents* / isolation & purification
Protective Agents* / pharmacology
Reactive Oxygen Species / metabolism
Skin / drug effects
Skin / metabolism
Skin / radiation effects
Skin Aging* / drug effects
Skin Aging* / radiation effects
Superoxide Dismutase / genetics
Superoxide Dismutase / metabolism
Ultraviolet Rays / adverse effects
Zebrafish
Substances
Polysaccharides
Reactive Oxygen Species
Protective Agents
Superoxide Dismutase
Malondialdehyde
Catalase
Matrix Metalloproteinase 1
Glutathione Peroxidase
Antioxidants
Caspase 3
Grants and funding
This work was supported by the Key Project of Science and Technology of Anhui Province (2023n06020008) and Educational Commission of Anhui Province of China (KJ2020A0051)
Key Project of Science and Technology of Anhui Province (2023n06020008) and Educational Commission of Anhui Province of China (KJ2020A0051)


Glucose-6-phosphatase catalytic subunit gene family

Glucose-6-phosphatase catalytic subunit gene family
Glucose-6-phosphatase catalytic subunit gene family
J Biol Chem. 2009 Oct 23;284(43):29241-5. doi: 10.1074/jbc.R109.025544. Epub 2009 Aug 20.
Authors
John C Hutton 1 , Richard M O'Brien
Affiliation
1 Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver, Aurora, Colorado 80045, USA.
PMID: 19700406
PMCID: PMC2785553
DOI: 10.1074/jbc.R109.025544
Abstract
Glucose-6-phosphatase catalyzes the hydrolysis of glucose 6-phosphate (G6P) to glucose and inorganic phosphate. It is a multicomponent system located in the endoplasmic reticulum that comprises several integral membrane proteins, namely a catalytic subunit (G6PC) and transporters for G6P, inorganic phosphate, and glucose. The G6PC gene family contains three members, designated G6PC, G6PC2, and G6PC3. The tissue-specific expression patterns of these genes differ, and mutations in all three genes have been linked to distinct diseases in humans. This minireview discusses the disease association and transcriptional regulation of the G6PC genes as well as the biological functions of the encoded proteins.
Publication types
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
MeSH terms
Animals
Carbohydrate Metabolism, Inborn Errors / enzymology*
Carbohydrate Metabolism, Inborn Errors / genetics
Carrier Proteins / genetics
Carrier Proteins / metabolism
Catalytic Domain / genetics
Endoplasmic Reticulum / enzymology*
Endoplasmic Reticulum / genetics
Gene Expression Regulation, Enzymologic*
Glucose-6-Phosphatase / genetics
Glucose-6-Phosphatase / metabolism*
Humans
Hydrolysis
Multigene Family*
Multiprotein Complexes / genetics
Multiprotein Complexes / metabolism
Mutation*
Organ Specificity
Transcription, Genetic / genetics
Substances
Carrier Proteins
Multiprotein Complexes
Glucose-6-Phosphatase
Grants and funding
P30 DK057516/DK/NIDDK NIH HHS/United States
P60 DK020593/DK/NIDDK NIH HHS/United States
R01 DK076027/DK/NIDDK NIH HHS/United States
DK052068/DK/NIDDK NIH HHS/United States
DK56374/DK/NIDDK NIH HHS/United States
P30 DK57516/DK/NIDDK NIH HHS/United States
R56 DK052068/DK/NIDDK NIH HHS/United States
DK076027/DK/NIDDK NIH HHS/United States
R01 DK061645/DK/NIDDK NIH HHS/United States
R01 DK056374/DK/NIDDK NIH HHS/United States
DK76027/DK/NIDDK NIH HHS/United States
R01 DK052068/DK/NIDDK NIH HHS/United States
P60 DK20593/DK/NIDDK NIH HHS/United States
DK61645/DK/NIDDK NIH HHS/United States


tf.raw_ops.NonMaxSuppressionV2 | TensorFlow v2.16.1

tf.raw_ops.NonMaxSuppressionV2 | TensorFlow v2.16.1
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initialize_all_tables
initialize_all_variables
initialize_local_variables
initialize_variables
is_variable_initialized
load_file_system_library
local_variables
local_variables_initializer
make_template
map_fn
min_max_variable_partitioner
model_variables
moving_average_variables
multinomial
name_scope
no_regularizer
norm
ones_initializer
ones_like
op_scope
orthogonal_initializer
pad
parse_example
parse_single_example
placeholder
placeholder_with_default
py_func
quantize_v2
random_normal_initializer
random_poisson
random_uniform_initializer
reduce_all
reduce_any
reduce_join
reduce_logsumexp
reduce_max
reduce_mean
reduce_min
reduce_prod
reduce_sum
report_uninitialized_variables
reset_default_graph
resource_variables_enabled
reverse_sequence
scalar_mul
scan
scatter_add
scatter_div
scatter_max
scatter_min
scatter_mul
scatter_nd_add
scatter_nd_sub
scatter_nd_update
scatter_sub
scatter_update
serialize_many_sparse
serialize_sparse
set_random_seed
setdiff1d
shape
size
space_to_batch
space_to_depth
sparse_add
sparse_concat
sparse_matmul
sparse_merge
sparse_placeholder
sparse_reduce_max
sparse_reduce_max_sparse
sparse_reduce_sum
sparse_reduce_sum_sparse
sparse_segment_mean
sparse_segment_sqrt_n
sparse_segment_sum
sparse_split
sparse_to_dense
squeeze
string_split
string_to_hash_bucket
string_to_number
substr
tables_initializer
to_bfloat