diff --git a/packages/codemode/src/interpreter/runtime.ts b/packages/codemode/src/interpreter/runtime.ts
index 84f4d7c53f7..2825e744b5f 100644
--- a/packages/codemode/src/interpreter/runtime.ts
+++ b/packages/codemode/src/interpreter/runtime.ts
@@ -1088,7 +1088,7 @@ class Interpreter<R> {
       }
 
       let declaration: { readonly pattern: AstNode; readonly mutable: boolean } | undefined
-      let assignmentName: string | undefined
+      let assignment: AstNode | undefined
 
       if (left.type === "VariableDeclaration") {
         const declarations = getArray(left, "declarations")
@@ -1098,8 +1098,13 @@ class Interpreter<R> {
 
         const declarator = asNode(declarations[0], "declarations[0]")
         declaration = { pattern: getNode(declarator, "id"), mutable: getString(left, "kind") !== "const" }
-      } else if (left.type === "Identifier") {
-        assignmentName = getString(left, "name")
+      } else if (
+        left.type === "Identifier" ||
+        left.type === "MemberExpression" ||
+        left.type === "ArrayPattern" ||
+        left.type === "ObjectPattern"
+      ) {
+        assignment = left
       } else {
         throw new InterpreterRuntimeError("Unsupported for...of binding.", left)
       }
@@ -1108,8 +1113,8 @@ class Interpreter<R> {
         if (declaration) {
           self.pushScope()
           yield* self.declarePattern(declaration.pattern, value, declaration.mutable, left)
-        } else if (assignmentName) {
-          self.setIdentifierValue(assignmentName, value, left)
+        } else if (assignment) {
+          yield* self.assignPattern(assignment, value, left)
         }
 
         const result = yield* self.evaluateStatement(body).pipe(
@@ -1507,6 +1512,16 @@ class Interpreter<R> {
         return this.evaluateUnaryExpression(node)
       case "AssignmentExpression":
         return this.evaluateAssignmentExpression(node)
+      case "SequenceExpression": {
+        const self = this
+        return Effect.gen(function* () {
+          let result: unknown
+          for (const expression of getArray(node, "expressions")) {
+            result = yield* self.evaluateExpression(asNode(expression, "expressions"))
+          }
+          return result
+        })
+      }
       case "CallExpression":
         return this.evaluateCallExpression(node)
       case "ArrowFunctionExpression":
diff --git a/packages/codemode/test/parity.test.ts b/packages/codemode/test/parity.test.ts
index 1831a7222df..5593831127a 100644
--- a/packages/codemode/test/parity.test.ts
+++ b/packages/codemode/test/parity.test.ts
@@ -464,6 +464,54 @@ describe("H5: builtin coercion functions work as array callbacks", () => {
   })
 })
 
+describe("for...of assignment destructuring", () => {
+  test("assigns entry pairs into predeclared variables", async () => {
+    expect(
+      await value(`
+      let key
+      let item
+      const out = []
+      for ([key, item] of Object.entries({ a: 1, b: 2 })) out.push(key + item)
+      return { key, item, out }
+    `),
+    ).toEqual({ key: "b", item: 2, out: ["a1", "b2"] })
+  })
+
+  test("assigns object patterns and defaults", async () => {
+    expect(
+      await value(`
+      let id
+      let label
+      const labels = []
+      for ({ id, label = "unknown" } of [{ id: 1 }, { id: 2, label: "two" }]) labels.push(label)
+      return { id, label, labels }
+    `),
+    ).toEqual({ id: 2, label: "two", labels: ["unknown", "two"] })
+  })
+})
+
+describe("sequence expressions", () => {
+  test("evaluate left to right and return the final value", async () => {
+    expect(await value(`let x = 0; const result = (x += 1, x *= 3, x + 2); return { x, result }`)).toEqual({
+      x: 3,
+      result: 5,
+    })
+  })
+
+  test("support comma-separated for-loop updates", async () => {
+    expect(
+      await value(`
+      const pairs = []
+      for (let left = 0, right = 3; left < right; left++, right--) pairs.push([left, right])
+      return pairs
+    `),
+    ).toEqual([
+      [0, 3],
+      [1, 2],
+    ])
+  })
+})
+
 describe("destructuring assignment", () => {
   test("assigns object and array patterns to existing bindings", async () => {
     expect(